Neu5Gca2, 6Galb1, 4GlcNAc

Neu5Gca2, 6Galb1, 4GlcNAc

Product Overview

Neu5Gcα2,6Galβ1,4GlcNAc is a defined sialylated trisaccharide consisting of N-glycolylneuraminic acid (Neu5Gc), galactose (Gal), and N-acetylglucosamine (GlcNAc). The glycan contains a terminal α2-6 linked Neu5Gc sialic acid, a biologically significant motif present in many mammalian glycoproteins and glycolipids.

Neu5Gc-containing glycans are widely studied for their role in glycan recognition and immune responses, particularly in comparative mammalian glycosylation. The α2-6 linkage is especially important in receptor–ligand interactions and lectin specificity, making this compound useful for investigating sialic-acid–dependent signaling, antibody recognition, and host–pathogen interactions. Its well-defined structure and high purity support reliable analytical and biochemical research applications.

Applications

• Glycobiology and glycomics research
• Lectin and receptor binding specificity studies
• Comparative mammalian glycosylation analysis
• Antibody recognition and epitope mapping
• Host–pathogen interaction investigations
• Sialyltransferase and enzyme activity assays
• Analytical reference standard for HPLC, LC-MS, and NMR

Key Features

• Contains α2-6 linked Neu5Gc sialic acid
• Biologically relevant glycan recognition motif
• Suitable for binding affinity and interaction analysis
• High purity and batch-to-batch reproducibility
• Compatible with chromatographic and mass spectrometry techniques

Storage & Handling

• Store at −20 °C in a tightly sealed container
• Protect from moisture and repeated freeze–thaw cycles
• Allow vial to reach room temperature before opening