sodium D-glycero-D-gulo-heptonate , CAS:31138-65-5

D-Glucoheptonic acid sodium salt dihydratea-D-Glucoheptonic acid sodium salt dihydrate is a diagnostic agent that can be used to diagnose myocardial infarct. It is a glycol ether with a molecular weight of 168, which is used in the preparation of diagnostic agents for the detection of cardiac lesions. The compound is also used as an excipient in pharmaceutical preparations. In addition, it has been shown to have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.Title:?Glucoheptonic AcidCAS Registry Number:?87-74-1CAS Name:?D-glycero-D-gulo-Heptonic acidAdditional Names:?a-glucoheptonic acid; glucosemonocarboxylic acid; glucomonocarbonic acidMolecular Formula:?C7H14O8Molecular Weight:?226.18Percent Composition:?C 37.17%, H 6.24%, O 56.59%Literature References:?Obtained by treating glucose with HCN yielding a cyanohydrin which is saponified to glucoheptonic acid: Kiliani,?Ber.?19,?769 (1886); Fischer,?Ann.?270,?71 (1892); Armestar,?C.A.?45,?2865 (1951). Process starting with calcium cyanide and glucose: Clevenot,?US?2735866?(1956 to Lab. Clevenot). Diagnostic use of?99mTc complexes in renal scintigraphy: R. E. Boyd?et al.,?Br. J. Radiol.?46,?604 (1973); in brain scanning: J. L?veill?et al.,?J. Nucl. Med.?18,?957 (1977); T. W. Ryerson?et al.,?Radiology?127,?429 (1978). Subacute toxicity study: L. Belbeck?et al.,?Can. J. Comp. Med.?45,?299 (1981).Properties:?Lactonizes upon evapn. The lactone forms large sweetish crystals, mp 145-148?. [a]D20?-56.0? (shows mutarotation). Sol in water.Melting point:?mp 145-148?Optical Rotation:?[a]D20?-56.0? (shows mutarotation)?Derivative Type:?Sodium saltCAS Registry Number:?31138-65-5Additional Names:?Gluceptate sodium; sodium glucoheptonateMolecular Formula:?C7H13NaO8Molecular Weight:?248.16Percent Composition:?C 33.88%, H 5.28%, Na 9.26%, O 51.58%Literature References:?Prepn from corn syrup: Behnke,?US?3022343?(1962 to Pfanstiehl Labs).Properties:?Crystals (a-form), dec 161?. [a]D20?+6.06? (c = 10 in H2O). Freely sol in water.Optical Rotation:?[a]D20?+6.06? (c = 10 in H2O)?Derivative Type:?Calcium saltAdditional Names:?Gluceptate calcium; calcium glucoheptonate; calcium glucosemonocarbonate; calcium glucomonocarbonateTrademarks:?Calciforte (Serolam); CalheptoseMolecular Formula:?C14H26CaO16Molecular Weight:?490.42Percent Composition:?C 34.29%, H 5.34%, Ca 8.17%, O 52.20%Literature References:?Prepn from Na salt: Holstein,?US?3033900?(1962 to Pfanstiehl Labs.).Properties:?Hygroscopic crystals, somewhat acrid taste, dec 200?. Sol in water.?Derivative Type:?Magnesium saltAdditional Names:?Magnesium glucoheptonate; magnesium glucosemonocarbonate; magnesium glucomonocarbonateTrademarks:?NavolinMolecular Formula:?C14H26MgO16Molecular Weight:?474.65Percent Composition:?C 35.43%, H 5.52%, Mg 5.12%, O 53.93%Literature References:?Prepn: Cipelli,?US?3063896?(1962 to Merck & Co.).Properties:?Water-sol crystals, pleasant taste.?Derivative Type:?Complex with?99mTcAdditional Names:?Technetium?99mTc gluceptate; technetium?99mTc gluheptonateTrademarks:?Glucoscan (DuPont); TechneScan gluceptate (Mallinckrodt)?Use:?Pharmaceutic aid.Therap-Cat:?99mTc complex as diagnostic aid (radioactive imaging agent).CAS Number31138-65-5Product NameD-glycero-D-gulo-Heptonic acid, monosodium saltIUPAC Namesodium;(2R,3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoateMolecular FormulaC7H13NaO8Molecular Weight248.16 g/molInChIInChI=1S/C7H14O8.Na/c8-1-2(9)3(10)4(11)5(12)6(13)7(14)15;/h2-6,8-13H,1H2,(H,14,15);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1InChI KeyFMYOMWCQJXWGEN-WYRLRVFGSA-MSMILESC(C(C(C(C(C(C(=O)[O-])O)O)O)O)O)O.[Na+]Canonical SMILESC(C(C(C(C(C(C(=O)[O-])O)O)O)O)O)O.[Na+]Isomeric SMILESC([C@H]([C@H]([C@@H]([C@H]([C@H](C(=O)[O-])O)O)O)O)O)O.[Na+]CAS No: 31138-65-5,13007-85-7 Synonyms: Glucoheptonic acid sodium saltSodium glucoheptonate dihydrate MDL No: MFCD00013425 Chemical Formula: C7H13O8Na Molecular Weight: 248.16