2-Fluoro-2-deoxy-D-glucose, CAS:29702-43-0

2-Deoxy-2-fluoro-D-glucose2-deoxy-2-fluoro-D-Glucose (2-FG) is a derivative of glucose with anticancer activity. It inhibits the growth of 143B osteosarcoma cells grown under normoxic and hypoxic conditions when used at concentrations of 6 and 24 mM.2-deoxy-2-fluoro-aldehydo-D-glucose is a 2-deoxy-2-fluoro-D-glucose and an aldehyde. It derives from an aldehydo-D-glucose.The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)CAS Number29702-43-0Product NameFludeoxyglucoseIUPAC Name(2R,3S,4R,5R)-2-fluoro-3,4,5,6-tetrahydroxyhexanalMolecular FormulaC6H11FO5Molecular Weight182.15 g/molInChIInChI=1S/C6H11FO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1InChI KeyAOYNUTHNTBLRMT-SLPGGIOYSA-NSMILESC(C(C(C(C(C=O)F)O)O)O)OSynonyms18F Fluorodeoxyglucose, 18F-FDG, 18FDG, 2 Fluoro 2 deoxy D glucose, 2 Fluoro 2 deoxyglucose, 2-Fluoro-2-deoxy-D-glucose, 2-Fluoro-2-deoxyglucose, F 18, Fludeoxyglucose, F 18, Fluorodeoxyglucose, F18, Fluorodeoxyglucose, Fludeoxyglucose F 18, Fluorine 18 fluorodeoxyglucose, Fluorine-18-fluorodeoxyglucose, Fluorodeoxyglucose F 18, Fluorodeoxyglucose F18, Fluorodeoxyglucose, 18FCanonical SMILESC(C(C(C(C(C=O)F)O)O)O)OIsomeric SMILESC([C@H]([C@H]([C@@H]([C@H](C=O)F)O)O)O)O
CAS No: 29702-43-0,86783-82-6 MDL No: MFCD00077527 Chemical Formula: C6H11FO5 Molecular Weight: 182.15COA:Name:?2-Deoxy-2-fluoro-D-glucose?CAS: 29702-43-0 or 86783-82-6? ? ??M.F.:?C6H11FO5? ? ??M.W.: 182.15ItemsStandardsResultsAppearanceWhite or off-white powderPositiveSolubilityReadily soluble in water andinsoluble in etherPositiveNMR and MSShould complyCompliesIdentificationIR and TLCPositiveLoss Weight On DrynessMax. 1%CompliesResidue on ignitionMax. 0.5%CompliesTLC?(15%H2SO4-C2H5OH)Should be one spotOne spotAssay TLCMin. 98%98.6%References:
1. Hutchinson PJ, et al., Acta Neurochir. Suppl. 2005, 95, 165-8