L-Iditol, also known as L-idit or D-dulcitol, belongs to the class of organic compounds known as sugar alcohols. These are hydrogenated forms of carbohydrate in which the carbonyl group (aldehyde or ketone, reducing sugar) has been reduced to a primary or secondary hydroxyl group. L-Iditol is soluble (in water) and a very weakly acidic compound (based on its pKa). L-Iditol has been detected in multiple biofluids, such as feces, urine, and blood. L-Iditol exists in all eukaryotes, ranging from yeast to humans. Outside of the human body, L-iditol can be found in a number of food items such as kai-lan, olive, lovage, and groundcherry. This makes L-iditol a potential biomarker for the consumption of these food products.
L-iditol is the L-enantiomer of iditol. It has a role as a fungal metabolite and a human metabolite. It is an enantiomer of a D-iditol.L-Iditol is a sugar alcohol that is found in small quantities in nature and is used as a food additive and pharmaceutical excipient. L-Iditol has been shown to inhibit the growth of bacteria such as Escherichia coli K-12 at concentrations of 0.1% to 1%. This compound was also shown to have a protective effect on human erythrocytes from oxidative damage. The long-term toxicity of L-Iditol has not been well studied, but it does not seem to be toxic when ingested in doses up to 2000 mg/kg body weight.CAS Number488-45-9Product NameL-IditolIUPAC Name(2S,3R,4R,5S)-hexane-1,2,3,4,5,6-hexolMolecular FormulaC6H14O6Molecular Weight182.17 g/molInChIInChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5+,6+/m0/s1InChI KeyFBPFZTCFMRRESA-UNTFVMJOSA-NSMILESC(C(C(C(C(CO)O)O)O)O)OSolubilitySoluble in DMSOSynonymsIditol; L-Iditol;Canonical SMILESC(C(C(C(C(CO)O)O)O)O)OIsomeric SMILESC([C@@H]([C@H]([C@@H]([C@H](CO)O)O)O)O)OCAS No: 488-45-9 MDL No: MFCD00064289 Chemical Formula: C6H14O6 Molecular Weight: 182.17