2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone

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Catalog No: A10GD-4066
Cas No: 132152-76-2
Properties: Mol Formula: C8H14N2O6, Mol Weight: 234.21
IUPAC Name: N-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-2-hydroxyimino-6-(hydroxymethyl)oxan-3-yl]acetamide
Synonym: N-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-2-hydroxyimino-6-(hydroxymethyl)oxan-3-yl]acetamide, Lognac, CHEMBL402605

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2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone

2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone is a farnesyltransferase inhibitor that belongs to the group of techniques. It is used in the diagnosis of relapsed and resistant multiple myeloma. This drug has been shown to be a potent inductor of apoptosis in vitro and in vivo through inhibition of protein synthesis. 2-Acetamido-2-deoxy-D-gluconhydroximo-1,5-lactone also inhibits the growth of tumor cells and can be used as a potential chemotherapeutic agent for pediatric patients with relapsed or resistant myeloma.

CAS Number132152-76-2
Product NameN-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-2-hydroxyimino-6-(hydroxymethyl)oxan-3-yl]acetamide
IUPAC NameN-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-2-hydroxyimino-6-(hydroxymethyl)oxan-3-yl]acetamide
Molecular FormulaC8H14N2O6
Molecular Weight234.207
InChIInChI=1S/C8H14N2O6/c1-3(12)9-5-7(14)6(13)4(2-11)16-8(5)10-15/h4-7,11,13-15H,2H2,1H3,(H,9,12)/b10-8-/t4-,5-,6-,7-/m1/s1
SMILESCC(=O)NC1C(C(C(OC1=NO)CO)O)O

CAS No: 132152-76-2
Synonyms: LogNAc
MDL No: MFCD00151695
Chemical Formula: C8H14N2O6
Molecular Weight: 234.207

References:
1. Horsch M., et al.,, Eur. J. Biochem., 1996, 237, p4762. Stubbs K., et.al.,, J. Biol. Chem., 2007, 282, p21382

2. MSDS

3. Tech Data Sheets/Manuals

Size

1 G, 100 MG, 5 G, Other

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