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Catalog No: A10GD-4089
Cas No: 61278-30-6
Properties: Mol Formula: C6H10O8, Mol Weight: 210.14
IUPAC Name: (2S)-2-[(2S,3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid;hydrate
Synonym: d-glucaro-1,4-lactone monohydrate, D-SACCHARIC ACID 1 4-LACTONE, D-Saccharic acid 1,4-lactone (hydrate)
D-Saccharic acid 1,4-lactone monohydrate (DSAL) has an ability to inhibit the activity of ?-glucuronidase enzyme. It also potentially inhibits Klotho deglycosylation of excitatory amino acid transporters (EAATs) and peptide transporters (PEPTs).
D-Saccharic acid 1,4-lactone is an inhibitor of ?-glucuronidase (IC50 = 45 ?M for the human enzyme). It is commonly used as a standard in the development of novel inhibitors of ?-glucuronidase. D-Saccharic Acid 1,4-lactone is also used to prevent the cleavage of glucuronides in plasma, serum, or urine by ?-glucuronidase in samples.
| CAS Number | 61278-30-6 |
| Product Name | (S)-2-((2S,3R,4R)-3,4-Dihydroxy-5-oxotetrahydrofuran-2-yl)-2-hydroxyacetic acid hydrate |
| IUPAC Name | (2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid;hydrate |
| Molecular Formula | C6H10O8 |
| Molecular Weight | 210.14 g/mol |
| InChI | InChI=1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11;/h1-4,7-9H,(H,10,11);1H2/t1-,2-,3+,4?;/m1./s1 |
| InChI Key | NPFKVZHSFSFLPU-QGBSHYGGSA-N |
| SMILES | C1(C(C(=O)OC1C(C(=O)O)O)O)O.O |
| Synonyms | 1,4-Lactone-D-glucaric Acid Monohydrate; |
| Canonical SMILES | C1(C(C(=O)OC1C(C(=O)O)O)O)O.O |
| Isomeric SMILES | [C@H]1([C@H](C(=O)O[C@@H]1[C@@H](C(=O)O)O)O)O.O |
CAS No: 61278-30-6 Synonyms: D-SaccharolactoneD-Saccharic acid 1,4-lactone monohydrate MDL No: MFCD00149334 Chemical Formula: C6H8O7?H2O Molecular Weight: 210.14 |
white to off-white crystalline powder |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
10 in stock
10 in stock
10 in stock
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