Fluorescein di-bD-glucopyranoside, FDglu, Fluorescein di-bD-glucopyranoside
Fluorescein di-bD-glucopyranoside is a fluorescent probe that binds to the glucosylceramide receptor. The in vitro assays showed that it inhibits amide hydrolase and fatty acid amide hydrolase activities. Fluorescein di-bD-glucopyranoside can also inhibit the enzyme activity of gamma-aminobutyric acid (GABA) transaminase and oxadiazole synthase. This compound is a selective inhibitor of CB2 receptor, which is expressed in primary cells and has been shown to be involved in inflammatory responses.
Fluorescein Di-(?-D-glucopyranoside) is an ultrasensitive fluorogenic substrate for measurement of ?-glucosidase activity in vivo or in vitro.
CAS Number | 129787-66-2 |
Product Name | 3′,6′-Bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3H-spiro [isobenzofuran-1,9′-xanthen]-3-one |
IUPAC Name | 3′,6′-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]spiro[2-benzofuran-3, 9′-xanthene]-1-one |
Molecular Formula | C32H32O15 |
Molecular Weight | 656.6 g/mol |
ikB | InChI=1S/C32H32O15/c33-11-21-23(35)25(37)27(39)30(45-21)42-13-5-7-17-19(9-13)44-20- 10-14(43-31-28(40)26(38)24(36)22(12-34)46-31)6-8-18(20)32(17)16-4-2-1- 3-15(16)29(41)47-32/h1-10,21-28,30-31,33-40H,11-12H2/t21-,22-,23-,24-,25+,26 +,27-,28-,30-,31-/m1/s1 |
InChI Key | ZTOBILYWTYHOJB-LWXMCBIJSA-N |
SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC6=C3C=CC( =C6)OC7C(C(C(C(O7)CO)O)O)O |
Canonical SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC6=C3C=CC( =C6)OC7C(C(C(C(O7)CO)O)O)O |
Isometric SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)O[C@H]5[C@@H]([C@H]([C@@ H]([C@H](O5)CO)O)O)O)OC6=C3C=CC(=C6)O[C@H]7[C@@H]([C@H]([C @@H]([C@H](O7)CO)O)O)O |
CAS No: 129787-66-2 Synonyms: FDGlu MDL No: MFCD00133328 Chemical Formula: C32H32O15 Molecular Weight: 656.59 | In Stock. |
References: 1. Kohen E, Kohen C, Hirschberg JG, Santus R, Grabowski G, Mangel W, Gatt S, Prince J,, Cell Biochem. Funct., 1993, 11, p167 |