Pasteurella multocida Chondroitin synthase (PmCS)

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Name	Pasteurella multocida Chondroitin synthase (PmCS)
Catalog No.	EN01026
E.C.	2.4.1.226

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Accepted Name
N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase.
Alternative Name(s)
Chondroitin glucuronyltransferase II.
Reaction catalysed
UDP-alpha-D-glucuronate + [protein]-3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine <=> UDP + [protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine UDP-alpha-D-glucuronate + [protein]-3-O-((beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3))(n)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine <=> UDP + [protein]-3-O-(beta-D-GlcA-(1->3)-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3))(n)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine
Comment(s)
Involved in the biosynthesis of chondroitin and dermatan sulfate. The human chondroitin synthetase is a bifunctional glycosyltransferase, which also has the EC 2.4.1.175 activity required for the synthesis of the chondroitin sulfate disaccharide repeats. Similar chondroitin synthase ‘copolymerases’ can be found in Pasteurella multocida and Escherichia coli. There is also another human protein with apparently only the 3-beta- glucuronosyltransferase activity.

2. MSDS

3. Tech Data Sheets/Manuals

Size	1 MG, 10 MG, 5 MG, Other

SKU: EN01026 Categories: Enzymes, Glycoenzymes Tags: Custom Products, Enzymes, Glycoenzymes

Name	α2,3-sialyltransferase; PmST1
Catalog Number	EN01002
E.C.	2.4.99.4
Product Description	E. coli recombinant α2,3-sialyltransferase from Pasteurella multocida (P-1059)
Unit Definition	One unit is defined as the amount of enzyme that catalyzes the formation of 1 µmol Siaα2,3Lac from CMP-Sia and lactose per minute at 37 °C.

Name	L-fucokinase-GDP-fucose pyrophos-phorylase;FKP
Product Code	EN01016
E.C.	2.7.1.52/2.7.7.30
Product Description	E. coli recombinant L-fucokinase/GDP-fucose pyrophosphorylase from Bacteroides fragilis
Unit Definition	One unit is defined as the amount of enzyme that catalyzes the formation of 1 μmol of Fuc-1-P from L-Fuc and ATP per minute at 37 °C.