UDP-GlcNAz.2Na

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Chemical NameUridine-5’-diphospho-N-azidoacetyl-α-D-glucosamine, Disodium Salt
SynonymsUDP-GlcNAz·2Na, UDP-N-Azidoacetylglucosamine Disodium Salt, UDP-GlcNAz Disodium
Molecular FormulaC17H24N6Na2O17P2
Molecular Weight692.33 g/mol (disodium salt)
CAS No.608514-41-6 (free acid)
AppearanceWhite to off-white lyophilized powder
Purity≥95% (HPLC)
SolubilitySoluble in water
Storage−20°C, protect from moisture and light
ApplicationAzido-modified analogue of UDP-GlcNAc; serves as a substrate for O-GlcNAc transferase (OGT) and N-acetylglucosaminyltransferases enabling metabolic and chemoenzymatic glycan labeling; the azidoacetyl handle permits bioorthogonal conjugation via copper-catalyzed azide–alkyne cycloaddition (CuAAC) and strain-promoted azide–alkyne cycloaddition (SPAAC); can be epimerized to UDP-GalNAz by UDP-galactose-4-epimerase (GALE); widely used in O-GlcNAc proteomics, glycan imaging, and selective probing of intracellular O-GlcNAcylation
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UDP-GlcNAz.2Na

Formula: C17H24N6O17P2Na2
CAS:
MW: 692.33
Purity: min 90% by HPLC

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