| Chemical Name | Uridine-5’-diphospho-2-alkyne-N-acetylglucosamine |
|---|---|
| Synonyms | UDP-GlcNAlk, UDP-2-Alkyne-GlcNAc, UDP-2-Alkyne-N-Acetylglucosamine |
| Molecular Formula | C19H27N3O17P2 |
| Molecular Weight | 645.40 g/mol |
| CAS No. | N/A — research-grade compound |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture and light |
| Application | Alkyne-modified nucleotide sugar donor substrate; used for remodeling of cell-surface glycans and O-GlcNAc profiling; the terminal alkyne handle enables bioorthogonal detection via copper-catalyzed azide–alkyne cycloaddition (CuAAC); less susceptible to epimerization than the corresponding GalNAc analog; applied in glycoproteomic profiling, glycan imaging, and metabolic labeling |
| Chemical Name | Uridine-5’-diphospho-N-acetyl-α-D-galactosamine, Disodium Salt |
|---|---|
| Synonyms | UDP-GalNAc·2Na, UDP-N-Acetylgalactosamine Disodium Salt, UDP-α-D-N-Acetylgalactosamine |
| Molecular Formula | C17H25N3Na2O17P2 |
| Molecular Weight | 651.32 g/mol (disodium salt) |
| CAS No. | 108320-87-2 |
| Appearance | White to off-white powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture |
| Application | Activated nucleotide sugar donor substrate for N-acetylgalactosaminyltransferases (GalNAc-Ts / ppGalNAc-Ts); initiates mucin-type O-linked glycosylation by transferring GalNAc to serine/threonine residues of proteins (Tn antigen formation); also involved in glycolipid biosynthesis, chondroitin sulfate chain elongation, and blood group A antigen synthesis; widely used in in vitro glycosylation assays and glycoengineering |
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