| Chemical Name | Uridine-5’-diphospho-N-azidoacetyl-α-D-galactosamine, Disodium Salt |
|---|---|
| Synonyms | UDP-GalNAz·2Na, UDP-N-Azidoacetylgalactosamine Disodium Salt, UDP-GalNAz Disodium |
| Molecular Formula | C17H24N6Na2O17P2 |
| Molecular Weight | 692.33 g/mol (disodium salt) |
| CAS No. | 653600-61-4 |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture and light |
| Application | Azido-modified analogue of UDP-GalNAc; serves as a substrate for N-acetylgalactosaminyltransferases (ppGalNAc-Ts) enabling metabolic and chemoenzymatic glycan labeling; the azidoacetyl handle permits bioorthogonal conjugation via copper-catalyzed azide–alkyne cycloaddition (CuAAC) and strain-promoted azide–alkyne cycloaddition (SPAAC); widely used in O-GalNAc glycoproteomics, mucin-type glycan imaging, and site-specific antibody–drug conjugate (ADC) construction |
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