(9H-Fluoren-9-yl)methyl ((2R,4S,5R,6S)-4-(benzyloxy)-2-((benzyloxy)methyl)-6-(ethylthio)-5-(2,2,2-trichloroacetamido)tetrahydro-2H-pyran-3-yl) carbonate

(9H-Fluoren-9-yl)methyl ((2R,4S,5R,6S)-4-(benzyloxy)-2-((benzyloxy)methyl)-6-(ethylthio)-5-(2,2,2-trichloroacetamido)tetrahydro-2H-pyran-3-yl) carbonate

Product Information

• CAS Number: Not  Available
• Catalog Number: A23-1066
• Molecular Formula: C₄₁H₄₀Cl₃NO₈S
• Molecular Weight: ~820.18 g/mol
• Purity: ≥ 98%

Description

This compound is a highly functionalized thioglycoside derivative featuring Fmoc protection, benzyl ether groups, and a trichloroacetamido functionality. It is designed as an advanced intermediate for carbohydrate synthesis, particularly in the preparation of amino sugar derivatives.

The ethylthio group at the anomeric position allows efficient activation under mild conditions for glycosylation reactions, while the Fmoc and benzyl groups provide orthogonal protection strategies. The trichloroacetamido group is especially useful for controlled conversion into amino functionalities in later synthetic steps.

Applications

• Synthesis of amino sugars and glycoconjugates
• Oligosaccharide assembly
• Glycopeptide and carbohydrate-based drug research
• Advanced glycochemistry and protective group strategy development

Key Features

• Orthogonally protected (Fmoc, benzyl system)
• Contains trichloroacetamido functionality for amino sugar synthesis
• Reactive thioglycoside donor (ethylthio group)
• High stereochemical purity and stability

Storage

• Store at 2–8°C
• Keep in a dry, inert atmosphere
• Protect from moisture and light

Safety Information

• For research use only
• Use appropriate PPE (gloves, lab coat, eye protection)
• Avoid inhalation, ingestion, and skin contact