2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl N-acetylserine

2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl N-acetylserine ;
STN Epitope N-acetate; 6-O-a-Sialyl-2-acetamido-2-deoxy-a-D-galactopyranosyl-1-O-L-serine, N acetate2-Acetamido-6-O-(a-2-N-acetylneuraminyl)-2-deoxy-a-D-galactopyranosyl N-acetylserine is a synthetic glycosaminoglycan, which is a complex carbohydrate. It is a monosaccharide with a saccharide chain that is linked by an acetamido group to the 2 position of the N-acetylneuraminic acid residue. This compound has been modified with methylation and fluorination on the sugar. The fluorination prevents this product from being hydrolyzed by enzymes such as beta galactosidase and alpha amylase, making it more stable in vivo.CAS Number385398-89-0Product NameSTn Epitope N-AcetateIUPAC Name5-acetamido-2-[[5-acetamido-6-[(2S)-2-acetamido-2-carboxyethoxy]-3,4-dihydroxyoxan-2-yl]methoxy]-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acidMolecular FormulaC??H??N?O??Molecular Weight641.58InChIInChI=1S/C24H39N3O17/c1-8(29)25-11(21(37)38)6-41-22-16(27-10(3)31)19(36)18(35)14(43-22)7-42-24(23(39)40)4-12(32)15(26-9(2)30)20(44-24)17(34)13(33)5-28/h11-20,22,28,32-36H,4-7H2,1-3H3,(H,25,29)(H,26,30)(H,27,31)(H,37,38)(H,39,40)/t11-,12?,13+,14?,15?,16?,17+,18?,19?,20?,22?,24?/m0/s1SMILESCC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OCC2C(C(C(C(O2)OCC(C(=O)O)NC(=O)C)NC(=O)C)O)O)OSynonyms6-O-?-Sialyl-2-acetamido-2-deoxy-?-D-galactopyranosyl-1-O-L-serine N-Acetate;N-Acetyl-O-[2-(acetylamino)-6-O-(N-acetyl-?-neuraminosyl)-2-deoxy-?-D-galactopyranosyl]-L-serine;