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Catalog No: A10GD-4575
Cas No: 13264-92-1
Properties: Mol Formula: C14H18N2O8, Mol Weight: 342.3
IUPAC Name: N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(2-nitrophenoxy)oxan-3-yl]acetamide
Synonym: 2-Nitrophenyl-N-acetyl-beta-D-glucosaminide, 2-Nitrophenyl 2-(acetylamino)-2-deoxy-b-D-Glucopyranoside, N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(2-nitrophenoxy)oxan-3-yl]acetamide
2-Nitrophenyl-N-acetyl-beta-D-glucosaminide is a fluorescent substrate that is used to measure the activity of TNF-?. It has been shown to be expressed in a variety of tissue types, including lung and brain. In order to evaluate the profiles of 2-NPBG, it was evaluated for its sensitivity to thiazole orange, tnf-?, and various other agents. The findings from this evaluation showed that the fluorescence intensity of 2-NPBG was sensitive to tnf-? and other cell signaling molecules. The spectrum of 2-NPBG has been quantified as being between 400 nm and 500 nm. This product can be used as a base line for measuring changes in fluorescence intensity caused by TNF-? or other molecules that activate cells.
| CAS Number | 13264-92-1 |
| Product Name | 2-Nitrophenyl 2-acetamido-2-deoxy-beta-D-glucopyranoside |
| IUPAC Name | N-[(2S,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(2-nitrophenoxy)oxan-3-yl]acetamide |
| Molecular Formula | C14H18N2O8 |
| Molecular Weight | 342.3 g/mol |
| InChI | InChI=1S/C14H18N2O8/c1-7(18)15-11-13(20)12(19)10(6-17)24-14(11)23-9-5-3-2-4-8(9)16(21)22/h2-5,10-14,17,19-20H,6H2,1H3,(H,15,18)/t10-,11-,12-,13-,14-/m1/s1 |
| InChI Key | PXMQUEGJJUADKD-DHGKCCLASA-N |
| SMILES | CC(=O)NC1C(C(C(OC1OC2=CC=CC=C2[N+](=O)[O-])CO)O)O |
| Canonical SMILES | CC(=O)NC1C(C(C(OC1OC2=CC=CC=C2[N+](=O)[O-])CO)O)O |
| Isomeric SMILES | CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC2=CC=CC=C2[N+](=O)[O-])CO)O)O |
CAS No: 13264-92-1 Synonyms: 2-Nitrophenyl N-acetyl-b-D-glucosamineo-Nitrophenyl 2-acetamido-2-deoxy-b-D-glucosideCNP-b-D-GlcNAc MDL No: MFCD00067648 Chemical Formula: C14H18N2O8 Molecular Weight: 342.3 |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
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