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Catalog No: A10GD-4441
Cas No: 28541-83-5
Properties: Mol Formula: C16H18O8, Mol Weight: 338.31
IUPAC Name: 4-methyl-7-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
Synonym: 4-methylumbelliferyl alpha-d-mannoside, 4-methylumbelliferyl a-d-mannopyranoside, 4-Methylumbelliferyl alpha-D-mannopyranoside
4-Methylumbelliferyl alpha-D-mannopyranoside (4-MU-a-D-Man) is a fluorogenic substrate used in activity assays for alpha-mannosidase. When it is hydrolyzed by alpha-mannosidase, it produces a fluorescent compound, 4-methylumbelliferone (4-MU). 4-MU-a-D-Man is often used in medical research to monitor the activity of alpha-mannosidase, which is important in lysosomal storage diseases. In addition, 4-Methylumbelliferyl alpha-D-mannopyranoside has been used to study the the activity of concanavalin A, a lectin that specifically binds to alpha-D-mannopyranosyl and alpha-D-glucopyranosyl residues on various glycoproteins. The use of this fluorogenic enzyme substrate permits study the degree of alpha-D-mannosidic linkage cleavage by the enzyme.
GC-204 is a selective inhibitor of carbonic anhydrase ix (caix).
| CAS Number | 28541-83-5 |
| Product Name | 4-METHYLUMBELLIFERYL-alpha-D-MANNOPYRANOSIDE |
| IUPAC Name | 4-methyl-7-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one |
| Molecular Formula | C16H18O8 |
| Molecular Weight | 338.31 g/mol |
| InChI | InChI=1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3 |
| InChI Key | YUDPTGPSBJVHCN-VMMWWAARSA-N |
| SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O |
| Solubility | Soluble in DMSO |
| Synonyms | 4-methylumbelliferone-alpha-D-galactoside, 4-methylumbelliferyl galactose, 4-methylumbelliferyl-alpha-D-galactopyranoside, 4-methylumbelliferyl-beta-D-galactopyranoside, 4-methylumbelliferyl-beta-D-galactoside, 4-methylumbelliferyl-galactopyranoside, 4-methylumbelliferyl-galactopyranoside, ((alpha-D)-galactopyranosyloxy)-isomer, 4-methylumbelliferyl-galactopyranoside, ((beta-D)-galactosyloxy)-isomer, 4-MUBF-GP |
| Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)OC3C(C(C(C(O3)CO)O)O)O |
| Isomeric SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)O[C@@H]3[C@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O |
CAS No: 28541-83-5 Synonyms: 4-MU-a-D-Man MDL No: MFCD00067662 Chemical Formula: C16H18O8 Molecular Weight: 338.31 |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
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