4-Methylumbelliferyl heptanoate
Fluorescent substrate for esterases and lipases. Also used to measure cell proliferation and viability.
4-Methylumbelliferyl heptanoate is a metabolic precursor of caproic acid and 17?-estradiol. It is used as a pharmacological agent to study the effects of drugs on the activity of enzymes in primary cells. This product has been shown to inhibit the activities of protease, lipase, and amylase. 4-Methylumbelliferyl heptanoate also inhibits IGF-I production by liver cells and body mass index. The mechanism for this inhibition may be due to its ability to cause cell lysis in adipose tissue, which leads to an increase in IGFBP-2 levels.
CAS Number | 18319-92-1 |
Product Name | 4-Methylumbelliferyl heptanoate |
IUPAC Name | (4-methyl-2-oxochromen-7-yl) heptanoate |
Molecular Formula | C17H20O4 |
Molecular Weight | 288.34 g/mol |
InChI | InChI=1S/C17H20O4/c1-3-4-5-6-7-16(18)20-13-8-9-14-12(2)10-17(19)21-15(14)11-13/h8-11H,3-7H2,1-2H3 |
InChI Key | FFNBFZWIBOIPIV-UHFFFAOYSA-N |
SMILES | CCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C |
Synonyms | 4-methylumbelliferone heptanoate, 4-methylumbelliferyl heptanoate, 4-MUH |
Canonical SMILES | CCCCCCC(=O)OC1=CC2=C(C=C1)C(=CC(=O)O2)C |