4-Methylumbelliferyl cholin phosphate
4-Methylumbelliferyl phosphocholine
4-Methylumbelliferyl phosphocholine (4MUPC) is a synthetic phenacyl ester that is used in the study of phospholipid metabolism. It binds to the enzyme phosphodiesterase, which is found in mammalian cells and has been shown to be activated by sodium taurocholate. This compound can be used to detect the presence of this enzyme in cell cultures. 4MUPC binds to a type strain of Clostridium perfringens, allowing it to be identified as a member of this species. The binding affinity is also strong enough for the detection of quinacrine-resistant strains of Clostridium perfringens. 4MUPC also binds to a monoclonal antibody that recognizes phosphatases, which are enzymes that hydrolyze phosphate esters and are involved in lipid metabolism.
CAS Number | 97055-84-0 |
Product Name | 4-Methylumbelliferyl Phosphocholine |
IUPAC Name | (4-methyl-2-oxochromen-7-yl) 2-(trimethylazaniumyl)ethyl phosphate |
Molecular Formula | C15H20NO6P |
Molecular Weight | 341.3 g/mol |
InChI | InChI=1S/C15H20NO6P/c1-11-9-15(17)21-14-10-12(5-6-13(11)14)22-23(18,19)20-8-7-16(2,3)4/h5-6,9-10H,7-8H2,1-4H3 |
InChI Key | XFDMHBWTKCGCSD-UHFFFAOYSA-N |
SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)OP(=O)([O-])OCC[N+](C)(C)C |
Synonyms | 2-[[Hydroxy[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]phosphinyl]oxy]-N,N,N-trimethylethanaminium Inner Salt; 4-MUPC; |
Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)OP(=O)([O-])OCC[N+](C)(C)C |