4-Nitrophenyl b-D-thiomannopyranoside
4-Nitrophenyl b-D-thiomannopyranoside acts as a substrate for β-mannosidase and thioglycoligase. Upon enzymatic cleavage, these substrates release 4-nitrophenol, a yellow chromophore that can be detected spectrophotometrically at 405 nm, facilitating quantitative measurements of enzymatic activity. Consequently, these substrates are widely used in biochemical research, clinical diagnostics, and drug discovery for evaluating the function of specific enzymes in various biological processes.
CAS Number |
55385-51-8 |
Product Name |
4-Nitrophenyl 1-thio-beta-D-mannopyranoside |
IUPAC Name |
(2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-(4-nitrophenyl)sulfanyloxane-3,4,5-triol |
Molecular Formula |
C12H15NO7S |
Molecular Weight |
317.32 g/mol |
InChI |
InChI=1S/C12H15NO7S/c14-5-8-9(15)10(16)11(17)12(20-8)21-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11+,12+/m1/s1 |
InChI Key |
IXFOBQXJWRLXMD-GCHJQGSQSA-N |
SMILES |
C1=CC(=CC=C1[N+](=O)[O-])SC2C(C(C(C(O2)CO)O)O)O |
Synonyms |
4-nitrophenyl 1-thio-beta-D-mannopyranoside, p-nitrophenyl 1-thio-beta-D-mannopyranoside, para-nitrophenyl 1-thio-beta-D-mannopyranoside |
Canonical SMILES |
C1=CC(=CC=C1[N+](=O)[O-])SC2C(C(C(C(O2)CO)O)O)O |
Isomeric SMILES |
C1=CC(=CC=C1[N+](=O)[O-])S[C@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O |
CAS No: 55385-51-8
Synonyms: PNP-1-thio-b-D-Man
MDL No: MFCD00211138
Chemical Formula: C12H15NO7S
Molecular Weight: 317.32
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