A2G1 N-Glycan refers to a specific type of N-glycan structure. In this case:
A2: Represents two antennae, meaning the N-glycan structure has two branching arms.
G1: Indicates that one of these arms terminates with a galactose residue.
N-Glycans are complex carbohydrates that are attached to proteins through asparagine (Asn) residues. They play crucial roles in protein folding, stability, and cellular recognition. The “A2G1” structure is commonly found in glycoproteins and is one of the many variations that can affect the biological functions of these molecules.
This type of glycan is often analyzed in glycomics research, particularly in the development of biologic drugs, as the glycosylation pattern can significantly influence the drug’s efficacy, safety, and immunogenicity.