D-(+)-Melibiose

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Cat Number : A14-1046

D-(+)-Melibiose is a disaccharide composed of one galactose and one glucose unit linked by an α(1→6) glycosidic bond. It is a reducing sugar that plays a significant role in various biological processes and is commonly used in microbiological studies.

Chemical Properties

  • CAS Number: 585-99-9
  • Molecular Formula: C₁₂H₂₄O₁₂
  • Molecular Weight: 360.31 g/mol

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D-(+)-Melibiose

D-(+)-Melibiose is a disaccharide composed of one galactose and one glucose unit linked by an α(1→6) glycosidic bond. It is a reducing sugar that plays a significant role in various biological processes and is commonly used in microbiological studies.

Chemical Properties

  • CAS Number: 585-99-9
  • MDL No.: MFCD00198191
  • Catalog Number: A831945
  • EINECS: 209-568-6
  • Molecular Formula: C₁₂H₂₄O₁₂
  • Molecular Weight: 360.31 g/mol
  • Boiling Point: 662.8 ± 55.0 °C at 760 mmHg
  • Melting Point: 182 °C (dec.) (lit.)
  • Flash Point: 354.6 ± 31.5 °C
  • Density: Not specified (typically around 1.68 g/cm³)
  • Appearance: White powder
  • Storage Conditions: Store at 2–8 °C for long-term stability (months).
  • Refractivity: 1.652

Physical Characteristics

D-(+)-Melibiose appears as a white crystalline powder and is soluble in water, making it suitable for various laboratory applications. Its melting point of approximately 182 °C indicates its thermal stability, while its high boiling point suggests that it can withstand elevated temperatures without decomposing.

Biological Significance

  1. Microbial Metabolism:
    • Melibiose serves as a carbon source for certain bacteria, particularly Saccharomyces pastorianus, which can metabolize melibiose, differentiating it from other species like Saccharomyces cerevisiae that cannot.
  2. Role in Gene Regulation:
    • It acts as an effector molecule that can activate the lac operon by binding to the repressor protein, facilitating the expression of genes involved in lactose metabolism.
  3. Prebiotic Potential:
    • Melibiose may have prebiotic effects, promoting the growth of beneficial gut bacteria and contributing to gut health.
  4. Research Applications:
    • Used in studies investigating carbohydrate interactions and the effects of sugar on microbial growth and metabolism.

Synthesis and Purification

D-(+)-Melibiose can be synthesized enzymatically or extracted from natural sources. It can be purified through crystallization techniques, often involving water or ethanol to achieve high purity levels.

Safety Profile

While D-(+)-melibiose is generally regarded as safe for laboratory use, standard safety protocols should be followed when handling this compound. Personal protective equipment (PPE) should be used to minimize exposure.

Conclusion

D-(+)-Melibiose (CAS No. 585-99-9) is an important disaccharide with applications in microbiology, biochemistry, and nutrition. Its role as a substrate for specific microorganisms and its function in gene regulation make it valuable for research and industrial applications.

Citations:

  1. https://www.chemicalbook.com/ChemicalProductProperty_EN_CB1322130.htm
  2. https://goldbio.com/product/7158/d-melibiose-monohydrate
  3. https://pubchem.ncbi.nlm.nih.gov/compound/Melibiose
  4. https://pubchem.ncbi.nlm.nih.gov/compound/440658
  5. https://en.wikipedia.org/wiki/Melibiose
  6. https://omanchem.com/product/D-MELIBIOSE-PURISS-99
  7. https://www.medchemexpress.com/d-melibiose.html
  8. https://www.lobachemie.com/Carbohydrates-04545/D-MELIBIOSE-CASNO-66009-10-7.aspx

 

2. MSDS

3. Tech Data Sheets/Manuals

Size

1 MG, 10 MG, 5 MG

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