Dodecanoyl D-Sucrose

Dodecanoyl D-Sucrose

Dodecanoyl D-Sucrose (CAS No. 25339-99-5) is a nonionic surfactant and a fatty acid ester of sucrose, known for its applications in various biochemical and industrial processes. Below is a detailed description of its chemical properties, physical characteristics, applications, and safety considerations.

Chemical Identification

• CAS Registry Number: 25339-99-5
• MDL Number: MFCD00077947
• EINECS: 246-873-3
• Molecular Formula: C24H44O12\text{C}_{24}\text{H}_{44}\text{O}_{12}C24H44O12
• Molecular Weight: 524.60 g/mol
• IUPAC Name: β-D-fructofuranosyl α-D-glucopyranoside monododecanoate
• Synonyms: Sucrose monododecanoate, Dodecanoyl sucrose

Physical Properties

Chemical Properties

Dodecanoyl D-sucrose is stable under normal conditions but should be stored at -20 °C for long-term stability. It exhibits surfactant properties, making it effective in solubilizing membrane proteins and forming stable emulsions.

Applications

1. Biochemical Research:
   • Used as a nonionic detergent for solubilizing membrane proteins while maintaining their native state.
   • Acts as a surfactant in various biochemical assays.
2. Pharmaceuticals:
   • Enhances transcutaneous immunization by increasing serum IgG levels when used with antigens.
   • Employed in drug delivery systems to improve the bioavailability of active compounds.
3. Food Industry:
   • Utilized as an emulsifier and stabilizer in food formulations.
4. Cosmetics:
   • Serves as an ingredient in topical formulations due to its emulsifying properties.
5. Industrial Applications:
   • Used to prepare stable foams and oil-in-water emulsions for various products.

Safety and Handling

• Hazards:
  • Considered hazardous until further information is available; may cause irritation upon contact with skin or eyes.
• Precautions:
  • Use personal protective equipment (PPE) such as gloves and goggles.
  • Avoid ingestion or inhalation; handle in a well-ventilated area.
  • Review the Safety Data Sheet (SDS) before use.

Key Notes

• Purity: Available at ≥95% purity (Catalog No. A877619).
• The melting point indicates its thermal stability, suitable for various experimental conditions.
• Regulatory status includes listings in chemical databases for research use.

Dodecanoyl D-sucrose’s unique properties make it a valuable compound in both research and industrial applications, particularly in the fields of biochemistry, pharmaceuticals, and food science.

Citations:

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC8003523/
2. https://caymanchem.com/pdfs/29982.pdf
3. https://www.caymanchem.com/product/29982
4. https://www.bocsci.com/product/dodecanoyl-d-sucrose-cas-25339-99-5-176650.html
5. https://www.biomol.com/products/chemicals/biochemicals/dodecanoyl-d-sucrose-cay29982-250
6. https://www.labchem.com.my/products/33215/Dodecanoyl-D-Sucrose-Cayman
7. https://www.biosynth.com/p/DD06810/25339-99-5-dodecanoyl-d-sucrose
8. https://www.sigmaaldrich.com/GB/en/product/mm/324374