Fluoresceincolchicine

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Catalog No: A10GD-4453
Cas No: 66091-34-7
Properties: Mol Formula: C41H34N2O10S, Mol Weight: 746.8
IUPAC Name: 1-(3′,6′-dihydroxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-5-yl)-3-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)thiourea
Synonym: colchicine fluorescein, 1-(3′,6′-dihydroxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-5-yl)-3-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)thiourea, DTXSID10984589

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Colchicine fluorescein

Fluoregenic form of colchicine for staining and inhibit assembly of tublin.

Colchicine fluorescein is a fluorescent colchicine analog that has been shown to be effective in the detection of human serum. This drug is not active and does not bind to DNA or RNA. It is used for the detection of cancer cells and measurement of cardiac function. Colchicine fluorescein binds to the cell membrane by interacting with p-glycoprotein and inhibits the efflux pump activity, causing dilations in the cells. Colchicine fluorescein can also be used as a substrate for photodecomposition and microscopy.

CAS Number 66091-34-7
Product Name Colchicine fluorescein
IUPAC Name 1-(3′,6′-dihydroxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-5-yl)-3-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)thiourea
Molecular Formula C41H34N2O10S
Molecular Weight 746.8 g/mol
InChI InChI=1S/C41H34N2O10S/c1-48-32-14-9-24-25(19-31(32)46)30(13-5-20-15-35(49-2)37(50-3)38(51-4)36(20)24)43-40(54)42-21-6-10-27-26(16-21)39(47)53-41(27)28-11-7-22(44)17-33(28)52-34-18-23(45)8-12-29(34)41/h6-12,14-19,30,44-45H,5,13H2,1-4H3,(H2,42,43,54)
InChI Key DQCILGJBPWFBHI-UHFFFAOYSA-N
SMILES COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=S)NC4=CC5=C(C=C4)C6(C7=C(C=C(C=C7)O)OC8=C6C=CC(=C8)O)OC5=O
Synonyms fluorescein colchicine
Canonical SMILES COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=S)NC4=CC5=C(C=C4)C6(C7=C(C=C(C=C7)O)OC8=C6C=CC(=C8)O)OC5=O

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3. Tech Data Sheets/Manuals

Size

1 G, 100 MG, 5 G, Other

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