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Catalog No: A10GD-4511
Cas No: 7298-65-9
Properties: Mol Formula: C28H24O7, Mol Weight: 472.5
IUPAC Name: (6′-butanoyloxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-3′-yl) butanoate
Synonym: Fluorescein, dibutyrate, (6′-butanoyloxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-3′-yl) butanoate, ONT4U528WD
Fluorogenic esterase and lipase substrate
Fluorescein dibutyrate is a pharmaceutical preparation that is used to treat certain types of cancer. It is a synthetic fluorophore that binds to DNA and RNA, which can be visualized by fluorescence microscopy. Fluorescein dibutyrate has been shown to inhibit the cellular production of ATP in human lymphocytes, as well as transposable elements in mouse erythrocytes. This agent has also been shown to inhibit protease activity in yeast cell extracts and to bind to nucleic acids with high affinity. Fluorescein dibutyrate is active against a variety of bacteria and fungi, including Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Aspergillus fumigatus, Saccharomyces cerevisiae, Saccharomyces kluyveri and Schizosaccharomyces pombe.
| CAS Number | 7298-65-9 |
| Product Name | Fluorescein dibutyrate |
| IUPAC Name | (6′-butanoyloxy-3-oxospiro[2-benzofuran-1,9′-xanthene]-3′-yl) butanoate |
| Molecular Formula | C28H24O7 |
| Molecular Weight | 472.5 g/mol |
| InChI | InChI=1S/C28H24O7/c1-3-7-25(29)32-17-11-13-21-23(15-17)34-24-16-18(33-26(30)8-4-2)12-14-22(24)28(21)20-10-6-5-9-19(20)27(31)35-28/h5-6,9-16H,3-4,7-8H2,1-2H3 |
| InChI Key | CGMHIZMGYHYHML-UHFFFAOYSA-N |
| SMILES | CCCC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)CCC)C5=CC=CC=C5C(=O)O3 |
| Synonyms | FLUORESCEIN DIBUTYRATE;FLUORESCEIN DIBUTYRATE, FOR FLUOR-ESCENC E;Dibutanoic acid 3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-3′,6′-diyl ester;Dibutyric acid 3′-oxospiro[9H-xanthene-9,1′(3’H)-isobenzofuran]-3,6-diyl ester;Butanoic acid, 1,1 |
| Canonical SMILES | CCCC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)CCC)C5=CC=CC=C5C(=O)O3 |
| Size | 1 G, 100 MG, 5 G, Other |
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