Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-β-D-arabinopentofuranoside

Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-β-D-arabinopentofuranoside

Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-β-D-arabinopentofuranoside, with CAS Number 197647-15-7, is a chemical compound notable for its application in research, particularly in the field of nucleoside analogues. Here is a detailed description of this compound:

Chemical Information

• Molecular Formula: C20H19FO5S
• Molecular Weight: 390.43 g/mol
• Purity: 97%
• Catalog Number: A944957

Description

This modified sugar nucleoside features a unique combination of a fluorine atom and a thio group, making it valuable for a range of biochemical applications. Its enhanced structure, including benzoyl groups, contributes to greater stability and improved solubility—key factors for effective use in laboratory research and drug development studies.

This compound is used primarily in the synthesis of oligonucleotides and nucleoside analogues, which may have potential therapeutic applications in antiviral and anticancer treatments.

Citations:

1. https://pubchem.ncbi.nlm.nih.gov/compound/15516162
2. https://academic.oup.com/nar/article/35/5/1441/1258854
3. https://synthose.com/products/DA257
4. https://patents.google.com/patent/EP3184112A1/en
5. https://www.medchemexpress.com/-5-di-o-benzoyl-2-fluoro-4-thio-d-arabinopentofuranoside.html
6. https://pubchem.ncbi.nlm.nih.gov/compound/54254411
7. http://lookchemical.com/Methyl2-deoxy-3_5-di-O-benzoyl-2-fluoro-4-thio-beta-D-arabinopentofuranoside/197647-15-7.html
8. https://www.semanticscholar.org/paper/856e58cefc34dd3343a52eb82b6700e955e94d98