Request a quote
Catalog No: A10GD-4237
Cas No: 2616-72-0
Properties: Mol Formula: C18H15ClNO5P, Mol Weight: 391.7
IUPAC Name: [3-[(4-chloro-2-methylphenyl)carbamoyl]naphthalen-2-yl] dihydrogen phosphate
Synonym: 3-((4-Chloro-2-methylphenyl)carbamoyl)naphthalen-2-yl dihydrogen phosphate, N-(4-Chloro-2-methylphenyl)-3-(phosphonooxy)naphthalene-2-carboxamide, NASTRp
Naphthol AS-TR phosphate is an experimental drug that inhibits the activity of proteases, which are enzymes that break down proteins. It was shown to have a high specificity for Onchocerca volvulus, a parasite that causes onchocerciasis in humans. Naphthol AS-TR phosphate has been shown to inhibit the expression of target genes in experimental infections with this parasite and has also been used to treat cancer. This drug is cell specific and can be used for histochemical staining by binding to phosphatase enzymes.
NASTRp is an inhibitor of CREB-CBP complex which possesses anti-cancer effects along with cell cycle regulation, autophagy suppression, and endoplasmic reticulum stress.
| CAS Number | 2616-72-0 |
| Product Name | N-(4-Chloro-2-methylphenyl)-3-(phosphonooxy)naphthalene-2-carboxamide |
| IUPAC Name | [3-[(4-chloro-2-methylphenyl)carbamoyl]naphthalen-2-yl] dihydrogen phosphate |
| Molecular Formula | C18H15ClNO5P |
| Molecular Weight | 391.7 g/mol |
| InChI | InChI=1S/C18H15ClNO5P/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24/h2-10H,1H3,(H,20,21)(H2,22,23,24) |
| InChI Key | SHTFMUPUBYXPCD-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)Cl)NC(=O)C2=CC3=CC=CC=C3C=C2OP(=O)(O)O |
| Solubility | Soluble in DMSO |
| Synonyms | naphthol AS-TR phosphate, NASTRp compound |
| Canonical SMILES | CC1=C(C=CC(=C1)Cl)NC(=O)C2=CC3=CC=CC=C3C=C2OP(=O)(O)O |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
Gal-a1,3-(Fuc-a1,2)-Gal-b1,4-Glc, CAS:59957-92-5, G06873PC
10 in stock
10 in stock
10 in stock
10 in stock
Glycodepot serve all your needs in glycoscience from products, services, networking and announcements. Get the best glycoscience products and services to support your research. Shop Now and learn about cutting-edge solutions in glycochemistry, glycobiology, and glyco-analysis!
