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Catalog No: A10GD-4486
Cas No: 70375-22-3
Properties: Mol Formula: C24H28ClN5O5, Mol Weight: 502
IUPAC Name: benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]carbamate;hydrochloride
Synonym: EINECS 274-586-3, Z-L-Arg 7-amido-4-methylcoumarin hydrochloride, Benzyl (S)-(4-(amidinoamino)-1-(((4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino)carbonyl)butyl)carbamate monohydrochloride
Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H. Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
N-alpha-CBZ-L-Arginine 7-amido-4-methylcoumarin hydrochloride is a fluorogenic substrate that is used as a ligand in enzyme assays, as well as an enzyme substrate in food and environmental testing. It has been shown to be useful in the detection of bacterial colonies on agar plates, with a sensitivity of 5 x 10 CFU/mL. N-alpha-CBZ-L-Arginine 7-amido-4-methylcoumarin hydrochloride can also be used for chemiluminescence detection of bacteria or for staining or bioluminescence detection of fungi.
| CAS Number | 70375-22-3 |
| Product Name | Benzyl (S)-(4-(amidinoamino)-1-(((4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino)carbonyl)butyl)carbamate monohydrochloride |
| IUPAC Name | benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]carbamate;hydrochloride |
| Molecular Formula | C24H28ClN5O5 |
| Molecular Weight | 465,50*36,45 g/mole |
| InChI | InChI=1S/C24H27N5O5.ClH/c1-15-12-21(30)34-20-13-17(9-10-18(15)20)28-22(31)19(8-5-11-27-23(25)26)29-24(32)33-14-16-6-3-2-4-7-16;/h2-4,6-7,9-10,12-13,19H,5,8,11,14H2,1H3,(H,28,31)(H,29,32)(H4,25,26,27);1H/t19-;/m0./s1 |
| InChI Key | JYWCRDUTYUBXOL-FYZYNONXSA-N |
| SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)OCC3=CC=CC=C3.Cl |
| Synonyms | Z-Arg-MCA;70375-22-3;Z-L-Arg7-amido-4-methylcoumarinhydrochloride;Z-L-Arginine-4-methyl-7-coumarinylamidehydrochloride;Carbobenzoxy-L-arginine-7-amino-4-methylcoumarinhydrochloride;N-alpha-CBZ-L-Arginine7-amido-4-methylcoumarinhydrochloride;Z-Arg-AmcHCl;Z-ARG-AMCHCL;C8022_SIGMA;SCHEMBL380911;EINECS274-586-3;FT-0629951;Nalpha-Cbz-L-arginine7-amido-4-methylcoumarinhydrochloride;Benzyl(S)-(4-(amidinoamino)-1-(((4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino)carbonyl)butyl)carbamatemonohydrochloride;Carbamicacid,[(1S)-4-[(aminoiminomethyl)amino]-1-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl]butyl]-,phenylmethylester,monohydrochloride(9CI) |
| Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)OCC3=CC=CC=C3.Cl |
| Isomeric SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CCCN=C(N)N)NC(=O)OCC3=CC=CC=C3.Cl |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
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