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| Chemical Name | Guanosine-5’-diphospho-6-azido-6-deoxy-L-fucose, Disodium Salt |
|---|---|
| Synonyms | GDP-6-N3-L-Fuc, GDP-6-Azido-Fucose, GDP-6-Azido-6-deoxy-L-Fucose |
| Molecular Formula | C16H22N8O15P2 · 2Na |
| Molecular Weight | 674.32 g/mol (disodium salt) |
| CAS No. | N/A — research-grade compound |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture and light |
| Application | Azido-modified nucleotide sugar donor substrate for fucosyltransferases; enables bioorthogonal click chemistry labeling of fucosylated glycans via azide–alkyne cycloaddition (CuAAC/SPAAC); used for glycan imaging and glycoproteomic profiling |
GDP-6-azido-6-deoxy-L-Fucose is a modified sugar nucleotide derivative of L-fucose, where the hydroxyl group at the 6th carbon position of the sugar has been replaced by an azido group (-N₃), and it is linked to guanosine diphosphate (GDP). This derivative is commonly used in chemical biology and glycobiology for metabolic labeling of glycans and studying fucosylation processes in cells.
The azido group makes it suitable for bioorthogonal click chemistry reactions, allowing researchers to tag or track fucosylated molecules with fluorescent or other labels.
| Size | 10 MG, 25 MG, 5 MG |
|---|
| Chemical Name | Uridine-5’-diphospho-N-azidoacetyl-α-D-glucosamine, Disodium Salt |
|---|---|
| Synonyms | UDP-GlcNAz·2Na, UDP-N-Azidoacetylglucosamine Disodium Salt, UDP-GlcNAz Disodium |
| Molecular Formula | C17H24N6Na2O17P2 |
| Molecular Weight | 692.33 g/mol (disodium salt) |
| CAS No. | 608514-41-6 (free acid) |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture and light |
| Application | Azido-modified analogue of UDP-GlcNAc; serves as a substrate for O-GlcNAc transferase (OGT) and N-acetylglucosaminyltransferases enabling metabolic and chemoenzymatic glycan labeling; the azidoacetyl handle permits bioorthogonal conjugation via copper-catalyzed azide–alkyne cycloaddition (CuAAC) and strain-promoted azide–alkyne cycloaddition (SPAAC); can be epimerized to UDP-GalNAz by UDP-galactose-4-epimerase (GALE); widely used in O-GlcNAc proteomics, glycan imaging, and selective probing of intracellular O-GlcNAcylation |
10 in stock
| Name | UDP-3-methyl-Glucose.2Na |
| Catalog No. | GN02024 |
| CAS Number | N/A |
| Formula | C16H24N2Na2O17P2 |
| M.W. | 624.29 |
10 in stock
| Name | UDP-2-F-Glucose.2Na |
| Catalog No. | GN02017 |
| CAS Number | 67341-43-9 |
| Formula | C15H21FN2Na2O16P2 |
| M.W. | 612.16 |
10 in stock
| Chemical Name | Uridine-5’-diphospho-6-azido-6-deoxy-D-glucose, Disodium Salt |
|---|---|
| Synonyms | UDP-6-N3-Glc·2Na, UDP-α-6N3-Glucose Disodium Salt, UDP-6-Azido-6-deoxy-D-Glucose Disodium Salt |
| Molecular Formula | C15H21N5O16P2 · 2Na |
| Molecular Weight | 635.28 g/mol (disodium salt) |
| CAS No. | 537039-67-1 |
| Appearance | White to off-white lyophilized powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture and light |
| Application | Azido-modified nucleotide sugar donor substrate for glucosyltransferases; the C6-azido handle enables bioorthogonal detection via copper-catalyzed azide–alkyne cycloaddition (CuAAC) and strain-promoted azide–alkyne cycloaddition (SPAAC); used for selective labeling of 5-hydroxymethylcytosine (5-hmC) in genomic DNA, glycan imaging, and glycoproteomic profiling |
10 in stock
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