2-Deoxy-2-fluoro-D-galactose (non-animal origin)

2-Deoxy-2-fluoro-D-galactose (non-animal origin) is a chemically synthesized fluorinated sugar analog derived from D-galactose, where the hydroxyl at the 2-position is replaced by a fluorine atom. This modification imparts enhanced metabolic stability and resistance to enzymatic degradation, important for medicinal chemistry and biochemical research. The compound is a white to off-white crystalline solid with a molecular formula of C6H11FO5 and a molecular weight of 182.15 g/mol. Its non-animal origin production ensures suitability for applications requiring animal-free materials. It is widely applied in glycosylation studies, enzyme mechanism probing, development of fluorinated glycomimetics, and radiolabeled tracer synthesis such as PET imaging agents. The compound is supplied with high purity (≥98%) confirmed by spectral and chromatographic analyses, free from microbial contamination due to its synthetic origin, and supported by identity and quality control documentation. Storage under refrigerated conditions (2-8 °C) maintains its stability, with a typical shelf life of 1-2 years.

Key features include its fluorine substitution at position 2 impacting biochemical pathways, and its reliable chemical and physical properties making it essential for drug development, diagnostic tracer synthesis, and advanced glycoscience research.

IUPAC Name

• (2R,3R,4R,5R,6R)-2-fluoro-2-deoxy-D-galactose

Appearance

• White to off-white crystalline powder

Molecular Weight

•  182.15 g/mol

Source

• Chemical synthesis, animal-free

Sugar Specificity

• Fluorinated D-galactose analog, glycosylation substrate

Biological Activity

• Metabolic stability, enzyme interaction probe

Purity

• ≥98% (NMR, HPLC)

Microbial Contamination

• Negligible

Identity & Quality Control

• Confirmed by NMR, MS, HPLC; COA supplied

Shelf Life and Storage

• Stable 1-2 years, stored 2-8 °C, dry and dark

Applications

• Medicinal chemistry, glycomimetic synthesis, PET tracers, enzymatic studies

Citations

• Pharmaffiliates
• ChemicalBook
• BOC Sciences
• TargetMol
• USBio
• ScienceDirect
• DrugBank
• FrontiersIn
• PMC
• Sigma-Aldrich