| Chemical Name | Uridine-5’-diphospho-N-acetyl-α-D-glucosamine, Disodium Salt |
|---|---|
| Synonyms | UDP-GlcNAc·2Na, UDP-N-Acetylglucosamine Disodium Salt, UDP-α-D-N-Acetylglucosamine |
| Molecular Formula | C17H25N3Na2O17P2 |
| Molecular Weight | 651.32 g/mol (disodium salt) |
| CAS No. | 91183-98-1 (disodium salt); 4578-31-8 (free acid) |
| Appearance | White to off-white powder |
| Purity | ≥95% (HPLC) |
| Solubility | Soluble in water |
| Storage | −20°C, protect from moisture |
| Application | Activated nucleotide sugar donor substrate for N-acetylglucosaminyltransferases (GnTs / OGT); end product of the hexosamine biosynthetic pathway (HBP) and a key metabolic sensor linking nutrient status to glycosylation; essential for N-glycan branching (GnT-I through GnT-V), O-GlcNAc modification of nuclear and cytoplasmic proteins, chitin biosynthesis, and peptidoglycan assembly; widely used in in vitro glycosylation assays, glycoengineering, and metabolic studies |
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