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Catalog No: A10GD-4726
Cas No: 10357-27-4
Properties: Mol Formula: C12H15NO8, Mol Weight: 301.25
IUPAC Name: (2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol
Synonym: 4-Nitrophenyl alpha-D-mannopyranoside, (2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol, 4-Nitrophenyl-alpha-D-mannopyranoside
4-Nitrophenyl a-D-mannopyranoside is a chromogenic pNP enzyme substrate that enables the detection and quantification of a-D-mannosidase activity in various biological samples through a colorimetric assay. The hydrolysis of the substrate by the enzyme releases 4-nitrophenol, a yellow compound whose absorption can be measured spectrophotometrically. Applications for this substrate span biomedical research, disease diagnostics, and industrial enzyme production.
CAS No: 10357-27-4 Synonyms: Man-a-PNP MDL No: MFCD00066002 Chemical Formula: C12H15NO8 Molecular Weight: 301.25 | In Stock |
| CAS Number | 10357-27-4 |
| Product Name | 4-Nitrophenyl a-D-mannopyranoside |
| IUPAC Name | (2R,3S,4S,5S,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol |
| Molecular Formula | C12H15NO8 |
| Molecular Weight | 301.25 g/mol |
| InChI | InChI=1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11+,12+/m1/s1 |
| InChI Key | IFBHRQDFSNCLOZ-GCHJQGSQSA-N |
| SMILES | C1=CC(=CC=C1[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)O |
| Synonyms | 4′-nitrophenyl-alpha-D-mannopyranoside, 4-nitrophenyl-alpha-D-mannopyranoside, alpha-PNM, p-nitrophenyl-alpha-mannoside, para-nitrophenyl-alpha-D-mannopyranoside, PNPAM |
| Canonical SMILES | C1=CC(=CC=C1[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)O |
| Isomeric SMILES | C1=CC(=CC=C1[N+](=O)[O-])O[C@@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O |
COA:
Name: 4-Nitrophenyl alpha-D-mannopyranoside
CAS: 10357-27-4 M.F.: C12H15NO8 M.W.: 301.25
Items | Standards | Results |
Appearance | White crystalline power | Positive |
Solubility | Soluble in water and insoluble in ether | Positive |
NMR and MS | Should comply | Complies |
Identification | IR and TLC | Positive |
M.P. | 180? -185? | 180? -184? |
[a]D [c=0.44 inH2O]. | +150o – +160o | +155.2o |
Loss Weight On Dryness | Max. 0.5% | Complies |
Beta-Isomer | Max. 0.5% | 0.4% |
TLC (15%H2SO4-C2H5OH) | One spot | Complies |
Assay (HPLC) | Min. 98% | 99.6% |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
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