Request a quote
Catalog No: A10GD-4456
Cas No: 217305-49-2
Properties: Mol Formula: C20H26N4O11P2, Mol Weight: 560.4
IUPAC Name: tetraazanium;(3-oxo-6′-phosphonatooxyspiro[2-benzofuran-1,9′-xanthene]-3′-yl) phosphate
Synonym: Fluorescein diphosphate tetraammonium salt, Fluorescein Diphosphate, Fluorescein diphosphate (tetraammonium)
Fluorescein diphosphate tetraammonium salt (FDPA) is a fluorescent dye used to determine the presence and concentration of calcium in biological samples. FDPA is also an experimental drug that blocks calcium release from intracellular stores by binding to the ryanodine receptor. This drug has been shown to be effective against coumarin derivatives and p-nitrophenyl phosphate, which are inhibitors of the enzyme phosphatase. The linear calibration curve of FDPA was found to be linear over a wide range of concentrations, with a phase transition temperature near 40?C. Biological samples used in this assay should be stored at 4?C or lower for best results.
Ultrasensitive fluorogenic alkaline phosphatase substrate. Hydrolysis produces the green fluorescent dye, fluorescein (Ex/Em = 490/520 nm).
Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases, sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluorescein monophosphate followed by strongly fluorescent fluorescein (excitation/emission ~490/514 nm).
| CAS Number | 217305-49-2 |
| Product Name | Fluorescein (tetraammonium) |
| IUPAC Name | tetraazanium;(3-oxo-6′-phosphonatooxyspiro[2-benzofuran-1,9′-xanthene]-3′-yl) phosphate |
| Molecular Formula | C20H26N4O11P2 |
| Molecular Weight | 560.4 g/mol |
| InChI | InChI=1S/C20H14O11P2.4H3N/c21-19-13-3-1-2-4-14(13)20(29-19)15-7-5-11(30-32(22,23)24)9-17(15)28-18-10-12(6-8-16(18)20)31-33(25,26)27;;;;/h1-10H,(H2,22,23,24)(H2,25,26,27);4*1H3 |
| InChI Key | YAPXZSKGRVJMLF-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OP(=O)([O-])[O-])OC5=C3C=CC(=C5)OP(=O)([O-])[O-].[NH4+].[NH4+].[NH4+].[NH4+] |
| Solubility | Soluble in DMSO |
| Synonyms | Fluorescein diphosphate; FDP; Fluorescein diphosphate Tetraammonium salt; |
| Canonical SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OP(=O)([O-])[O-])OC5=C3C=CC(=C5)OP(=O)([O-])[O-].[NH4+].[NH4+].[NH4+].[NH4+] |
| Size | 1 G, 100 MG, 5 G, Other |
|---|
10 in stock
10 in stock
10 in stock
IUPAC:Fuc(a1-2)[GalNAc(a1-3)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)b-Glc, G82858KU
10 in stock
Glycodepot serve all your needs in glycoscience from products, services, networking and announcements. Get the best glycoscience products and services to support your research. Shop Now and learn about cutting-edge solutions in glycochemistry, glycobiology, and glyco-analysis!
