Luteolin 7-O-Rutinoside

Luteolin 7-O-Rutinoside

Luteolin 7-O-rutinoside, with the CAS number 20633-84-5, is a flavonoid glycoside derived from various plants, including Vernonia bugulifolia and Artichoke. This compound is recognized for its diverse biological activities and potential health benefits, making it an area of interest in both nutritional science and pharmacology.

Chemical Identity

• CAS Number: 20633-84-5
• MDL Number: Not specified
• Molecular Formula: C27H30O15
• Molecular Weight: 594.52 g/mol
• EINECS Number: Not specified

Physical and Chemical Properties

1. Appearance: Typically appears as a yellow to orange powder.
2. Boiling Point: Approximately 954.0 ± 65.0 °C at 760 mmHg, indicating high thermal stability.
3. Melting Point: No data available, but it is expected to be stable under standard laboratory conditions.
4. Flash Point: 316.9 ± 27.8 °C, suggesting it is not easily flammable.
5. Density: Approximately 1.8 ± 0.1 g/cm³, indicating a relatively high density for an organic compound.

Biological Activities

Luteolin 7-O-rutinoside exhibits several significant biological properties:

1. Antioxidant Activity: It has been shown to scavenge free radicals, which may help protect cells from oxidative stress and reduce the risk of chronic diseases.
2. Anti-inflammatory Effects: This compound has demonstrated potential in reducing inflammation, making it beneficial for conditions such as arthritis.
3. Antimicrobial Properties: Luteolin 7-O-rutinoside has shown activity against various pathogens, suggesting its use in combating infections.
4. Antimutagenic Effects: Research indicates that it may inhibit mutagenesis in certain bacterial strains, highlighting its potential role in cancer prevention.
5. Metalloprotease Inhibition: It acts as a metalloprotease inhibitor, which could have implications in treating diseases where these enzymes play a crucial role.

Applications

Luteolin 7-O-rutinoside has various applications across different fields:

1. Pharmaceuticals: Its biological activities make it a candidate for developing supplements or medications aimed at reducing inflammation and oxidative stress.
2. Food Industry: Used as a natural antioxidant and preservative in food products to enhance shelf life and quality.
3. Nutraceuticals: Incorporated into dietary supplements for its potential health benefits related to inflammation and oxidative damage.
4. Research: Utilized in studies investigating the effects of flavonoids on health and disease mechanisms.

Safety Information

While Luteolin 7-O-rutinoside is generally regarded as safe for consumption in moderate amounts found in foods, standard safety practices should be observed when handling the compound in laboratory settings:

• Use appropriate personal protective equipment (PPE) when handling the substance.
• Store in a cool, dry place away from direct sunlight to maintain stability.

Citations:

1. https://www.chemfaces.com/natural/Luteolin-7-rutinoside-CFN93556.html
2. https://www.extrasynthese.com/flavone/1307-luteolin-7-o-rutinoside.html
3. https://www.medchemexpress.com/Luteolin-7-rutinoside.html
4. https://www.sigmaaldrich.com/IN/en/product/sigma/smb00200
5. https://www.biosynth.com/p/FL158250/20633-84-5-luteolin-7-rutinoside
6. https://www.caymanchem.com/product/34035/luteolin-7-o-rutinoside
7. https://ontosight.ai/glossary/term/luteolin-7-o-rutinoside-overview–679e223f38099fda3cfe5597
8. https://www.usbio.net/biochemicals/453986/Luteolin-7ORutinoside