8-Hydroxyquinolineglucuronide

8-Hydroxyquinoline b-D-glucuronide sodium salt 8-Hydroxyquinoline-b-D-glucuronide is a hydroxy derivative of 8-hydroxyquinoline that is produced by the glucuronidation of 8-hydroxyquinoline in rat liver microsomes. This compound has been shown to have genotoxic activity and carcinogenic potential in a model system. The optimum pH for its activity is between 6 and 7.8, with an optimum temperature of 37 degrees Celsius. CAS Number 14683-61-5 Product Name 8-Hydroxyquinoline glucuronide IUPAC Name (2S,3S,4S,5R)-3,4,5-trihydroxy-6-quinolin-8-yloxyoxane-2-carboxylic acid Molecular Formula C15H15NO7 Molecular Weight 321.28 g/mol InChI InChI=1S/C15H15NO7/c17-10-11(18)13(14(20)21)23-15(12(10)19)22-8-5-1-3-7-4-2-6-16-9(7)8/h1-6,10-13,15,17-19H,(H,20,21)/t10-,11-,12+,13-,15?/m0/s1 InChI Key DPEGQJDYRIQRHI-HXMBFPRCSA-N SMILES C1=CC2=C(C(=C1)OC3C(C(C(C(O3)C(=O)O)O)O)O)N=CC=C2 Synonyms 8-HQG, 8-hydroxy-quinolyl-glucuronide, 8-hydroxyquinoline glucuronide, 8-hydroxyquinoline-beta-D-glucuronide, 8-hydroxyquinolyl glucoronide, 8-OHQ-GlcA Canonical SMILES C1=CC2=C(C(=C1)OC3C(C(C(C(O3)C(=O)O)O)O)O)N=CC=C2 Isomeric SMILES C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)N=CC=C2 CAS No: 207728-71-0,14683-61-5 Synonyms: HQG8-Hydroxy-1-azanaphthalene-b-D-glucopyranosiduronic acid sodium salt MDL No: MFCD02683911 Chemical Formula: C15H14NNaO7 Molecular Weight: 343.26