NaphtholAS-BIN-acetyl-beta-D-glucosaminide

Naphthol AS-BI N-acetyl-b-D-glucosaminide Naphthol AS-BI N-acetyl-b-D-glucosaminide is an enzyme inhibitor that is used in the treatment of Gaucher's disease. The enzyme it inhibits is ?-glucosidase, which breaks down glucocerebrosides in the lysosomes of cells. This drug prevents the breakdown of glucocerebrosides and increases their concentration in cells, which reduces the symptoms of Gaucher's disease. Naphthol AS-BI N-acetyl-b-D-glucosaminide has been shown to be effective against wild type and mutant forms of the enzyme. However, it does not work against patients who are homozygous for a mutation in exon 1 of the ?glu gene that codes for ?glu protein. Naphthol AS-BI N-acetyl-beta-D-glucosaminide is a compound that has been widely studied in the field of biomedical research due to its numerous potential applications in medicine and related fields. In this paper, we will provide an overview of the physical and chemical properties, synthesis and characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, current state of research, potential implications in various fields of research and industry, limitations, and future directions of Naphthol AS-BI N-acetyl-beta-D-glucosaminide. CAS Number 3395-37-7 Product Name Naphthol AS-BI N-acetyl-beta-D-glucosaminide IUPAC Name 3-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7-bromo-N-(2-methoxyphenyl)naphthalene-2-carboxamide Molecular Formula C26H27BrN2O8 Molecular Weight 575.4 g/mol InChI InChI=1S/C26H27BrN2O8/c1-13(31)28-22-24(33)23(32)21(12-30)37-26(22)36-20-11-14-7-8-16(27)9-15(14)10-17(20)25(34)29-18-5-3-4-6-19(18)35-2/h3-11,21-24,26,30,32-33H,12H2,1-2H3,(H,28,31)(H,29,34)/t21-,22-,23-,24-,26-/m1/s1 InChI Key DMLKUPXKUQREOC-CFXNPWLASA-N SMILES CC(=O)NC1C(C(C(OC1OC2=C(C=C3C=C(C=CC3=C2)Br)C(=O)NC4=CC=CC=C4OC)CO)O)O Canonical SMILES CC(=O)NC1C(C(C(OC1OC2=C(C=C3C=C(C=CC3=C2)Br)C(=O)NC4=CC=CC=C4OC)CO)O)O Isomeric SMILES CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC2=C(C=C3C=C(C=CC3=C2)Br)C(=O)NC4=CC=CC=C4OC)CO)O)O