Phenyl1-thio-beta-D-galactopyranoside

Phenyl b-D-thiogalactopyranoside Phenyl b-D-thiogalactopyranoside is a carbohydrate binding agent that has been shown to have anti-cancer properties. It binds to galectin, a carbohydrate receptor on the surface of tumour cells, thereby interfering with cell proliferation and tumor growth. Phenyl b-D-thiogalactopyranoside also blocks the activity of glycolytic enzymes and can be used as an adjuvant in cancer therapy. This molecule is synthesized by nature or chemically by means of alkylation of phenol. The chemical synthesis is more efficient and economical than the natural process. CAS Number 16758-34-2 Product Name Phenyl 1-thio-beta-D-galactopyranoside IUPAC Name (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-phenylsulfanyloxane-3,4,5-triol Molecular Formula C12H16O5S Molecular Weight 272.32 g/mol InChI InChI=1S/C12H16O5S/c13-6-8-9(14)10(15)11(16)12(17-8)18-7-4-2-1-3-5-7/h1-5,8-16H,6H2/t8-,9+,10+,11-,12+/m1/s1 InChI Key OVLYAISOYPJBLU-IIRVCBMXSA-N SMILES C1=CC=C(C=C1)SC2C(C(C(C(O2)CO)O)O)O Synonyms Phenyl 1-Thio-?-D-galactopyranoside; Ph-thio-?-D-Gal Canonical SMILES C1=CC=C(C=C1)SC2C(C(C(C(O2)CO)O)O)O Isomeric SMILES C1=CC=C(C=C1)S[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)O CAS No: 16758-34-2 MDL No: MFCD00063272 Chemical Formula: C12H16O5S Molecular Weight: 272.32 COA: Name : Phenyl 1-thio-b-D-galactopyranoside CAS : 16758-34-2 M.F. : C 12 H 16 O 5 S M.W. : 272.32 Items Standards Results Appearance White or slightly yellowish crystalline power Positive Solubility Soluble in water and insoluble in ether Positive NMR and MS Should comply Complies Identification IR and TLC Positive M.P. 110 ? ~ 120 ? 115 ? -120 ? [a] D [c=0.88 inCH 3 OH]. -44 o ~ -46 o -44.2 o Loss Weight On Dryness Max. 1% Complies Alpha-Isomer Max. 0.5% 0 TLC (15%H 2 SO 4 -C 2 H 5 OH) One spot Complies Assay Min. 98% 98.4%