Fructose 1,6-bisphosphate aldolase (SMALDO)

Fructose 1,6-bisphosphate aldolase (SMALDO) Accepted Name Fructose-bisphosphate aldolase. Alternative Name(s) Aldolase. D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase. Fructose-1,6-bisphosphate triosephosphate-lyase. Reaction catalysed D-fructose 1,6-bisphosphate  <=>  glycerone phosphate  +  D-glyceraldehyde 3-phosphate Cofactor(s) Zn(2+). Comment(s) Also acts on (3S,4R)-ketose 1-phosphates. The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc. Formerly EC 4.1.2.7.