Peptide-N4-(N-acetyl-β-glucosaminyl) asparagineamidase (PNGaseF)

Peptide-N4-(N-acetyl-β-glucosaminyl) asparagineamidase (PNGaseF) Accepted Name Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase. Alternative Name(s) Glycopeptidase. Glycopeptide N-glycosidase. N-glycanase. N-oligosaccharide glycopeptidase. Reaction catalysed Hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue Comment(s) Does not act on (GlcNAc)-Asn, because it requires the presence of more than two amino-acid residues in the substrate (cf. EC  3.5.1.26 ). Formerly EC 3.2.2.18.