Glucose PEG Succinimidyl Carboxymethyl Ester

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Name Glucose PEG Succinimidyl Carboxymethyl Ester
Catalog No. A14-1001
CAS Number NA
Formula NA
M.W. MW 35000 (GLUC-SCM-35K)

 

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Glucose PEG Succinimidyl Carboxymethyl Ester is a high quality amine reactive PEG product with a succinimidyl carboxymethyl ester active group and a targeting glucose group. Glucose PEG Succinimidyl Carboxymethyl Ester reacts with amine group of lysine(s) at room temperature in less than 1hr, at pH 7-8. The presence of the monosaccharide sugar group (Glucose) increases significantly the selectivity of the PEGylation reaction.

References:

  1. Wei, G, et al., Glucose Transporter 1 (GLUT1)-Targeting and Hypoxia-Activated Mitochondria-Specific Chemo-thermal Therapy via a Glycosylated Poly (amido amine)/Celastrol (PAMAM/Cel) Complex. Journal of Colloid and Interface Science. 2021.
  2. He, H., et al., Development of mannose functionalized dendrimeric nanoparticles for targeted delivery to macrophages: use of this platform to modulate atherosclerosis, Translational Research, 2018, Vol. 193, P. 13-30.
  3. Drappier, C., pH-Responsive Surface Shielding By Electrostatic Adsorption of PEG Segments With Anionic Chain End, Universite Bordeaux, 2013.
  4. Weaver, E.A., et al., Effects of Shielding Adenoviral Vectors with Polyethylene Glycol on Vector-Specific and Vaccine-Mediated Immune Responses, Human Gene Therapy 2008, 19:1369–1382.

2. MSDS

3. Tech Data Sheets/Manuals

Size

1 G, 10 G, Other

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