Neu5Gca2, 6Galb1, 4GlcNAc

Neu5Gca2, 6Galb1, 4GlcNAc Product Overview Neu5Gcα2,6Galβ1,4GlcNAc is a defined sialylated trisaccharide consisting of N-glycolylneuraminic acid (Neu5Gc), galactose (Gal), and N-acetylglucosamine (GlcNAc). The glycan contains a terminal α2-6 linked Neu5Gc sialic acid , a biologically significant motif present in many mammalian glycoproteins and glycolipids. Neu5Gc-containing glycans are widely studied for their role in glycan recognition and immune responses, particularly in comparative mammalian glycosylation. The α2-6 linkage is especially important in receptor–ligand interactions and lectin specificity, making this compound useful for investigating sialic-acid–dependent signaling, antibody recognition, and host–pathogen interactions . Its well-defined structure and high purity support reliable analytical and biochemical research applications. Applications Glycobiology and glycomics research Lectin and receptor binding specificity studies Comparative mammalian glycosylation analysis Antibody recognition and epitope mapping Host–pathogen interaction investigations Sialyltransferase and enzyme activity assays Analytical reference standard for HPLC, LC-MS, and NMR Key Features Contains α2-6 linked Neu5Gc sialic acid Biologically relevant glycan recognition motif Suitable for binding affinity and interaction analysis High purity and batch-to-batch reproducibility Compatible with chromatographic and mass spectrometry techniques Storage & Handling Store at −20 °C in a tightly sealed container Protect from moisture and repeated freeze–thaw cycles Allow vial to reach room temperature before opening