Acetyl-D-lactosamine , Cas:77304-67-7

A natural structural element in a variety of glycoconjugates. Substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar and for characterizing lectins.N-acetyl-D-Lactosamine is a disaccharide consisting of galactose and N-acetylglucose. It occurs naturally as a structural element in a variety of glycoconjugates. N-acetyl-D-Lactosamine is used to characterize lectins. 2 N-Acetyllactosamine, also known as galb1-4glcnacb or lacnac, belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group. N-Acetyllactosamine is soluble (in water) and a very weakly acidic compound (based on its pKa). N-Acetyllactosamine has been found in human epidermis, spleen and intestine tissues. Within the cell, N-acetyllactosamine is primarily located in the cytoplasm. N-Acetyllactosamine can be converted into beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminide. N-acetyllactosamine is a beta-D-galactopyranosyl-(1->4)-N-acetyl-D-glucosamine having beta-configuration at the reducing end anomeric centre. CAS?: 32181-59-2 ??: LacNAcGalactopyranosyl-b-1,4-N-acetyl-D-glucosamine2-Acetamido-2-deoxy-D-lactoseGalb1-4GlcNAc MDL?: MFCD00063785 ???: C14H25NO11 ???: 383.35????: 1. Gunnarsson A, et al., Infect. Immun. 1984, 45, p412. Loomes LM, et al., Nature 1984, 307, p5603. J. Biol. Chem. 1981, 256, 104564. Anal. Chem. 1996, 68, 2573-25795. J. Am. Soc. Nephrol. 2015, 26, 2213-2221