D-Glycero-D-mannoheptose, CAS:1961-73-5

D-Glycero-D-manno-heptoseD-Glycero-D-manno-heptose is a glycosyl compound that belongs to the group of antimicrobial agents. It was first isolated from broth culture of E. coli K-12 and found to have strong activity against S. aureus, S. typhi, and other Gram-positive bacteria. D-Glycero-D-manno-heptose has been shown to inhibit the enzyme phosphatase in human serum and monoclonal antibody. It also has been shown to have a basic structure with phosphate groups on both ends of the molecule that may be involved in hydrogen bonding interactions with other molecules in vitro assays. The chemical structure of D-Glycero-D-manno-heptose is similar to polymyxin B and fluorescence probes, which are used as antibiotics or fluorescent labels respectively.CAS Number1961-73-5Product Name(2S,3S,4R,5R,6R)-2,3,4,5,6,7-HexahydroxyheptanalIUPAC Name(2S,3S,4R,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanalMolecular FormulaC7H14O7Molecular Weight210.18186InChIInChI=1S/C7H14O7/c8-1-3(10)5(12)7(14)6(13)4(11)2-9/h1,3-7,9-14H,2H2/t3-,4-,5-,6-,7+/m1/s1SMILESC(C(C(C(C(C(C=O)O)O)O)O)O)OCAS No: 1961-73-5 MDL No: MFCD00171225 Chemical Formula: C7H14O7 Molecular Weight: 210.182References: 1. Kneidinger B, Graninger M, Puchberger M, et al., J. Biol. Chem. 2001, 276, 24, p209352. Brimacombe JS, Kabir KMS, Carbohydr. Res. 1986, 152, p329