D-Mannosamine, 2-Amino-2-deoxy-D-mannose, CAS:2636-92-2

2-??-2-??-D-????D-????, 2-Amino-2-DeoxymannoseMannosamine (Man, 2-Amino-2-Deoxymannose) has the axial hydroxyl group at position 2 replaced by an amino group (Collins, 2006). Mannosamine has importance in the biosynthesis of sialic acids as they are synthesized by the condensation of D-mannosamine with pyruvic acid. Mannosamine has been found to have antitumor activity on human leukemia T-cell lines (Onoda, 1985). Mannosamine was also reported to inhibit glycosylphosphatidylinositol (GPI) synthesis in trypanosomes (Eckert, 1999).CAS Number2636-92-2Product Name2-Amino-2-deoxymannoseIUPAC Name(2S,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanalMolecular FormulaC6H13NO5Molecular Weight179.17 g/molInChIInChI=1S/C6H13NO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2,7H2/t3-,4-,5-,6-/m1/s1InChI KeyFZHXIRIBWMQPQF-KVTDHHQDSA-NSMILESC(C(C(C(C(C=O)N)O)O)O)OSynonyms2-amino-2-deoxymannose, D-mannosamine, mannosamine, mannosamine hydrochloride, (D)-isomer, mannosamine, (D)-isomerCanonical SMILESC(C(C(C(C(C=O)N)O)O)O)OIsomeric SMILESC([C@H]([C@H]([C@@H]([C@@H](C=O)N)O)O)O)O