L-Threose, CAS:95-44-3

L-ThreoseL-Threose is a sugar molecule that is used as a structural component of DNA and RNA. It is also an important part of the energy metabolism in cells. L-Threose can be enzymatically inactivated by glycosidases, which are enzymes that hydrolyze glycosidic bonds. The inhibition of glycosidases by L-threose may be useful for the prevention or treatment of diseases associated with enzyme activity, such as diabetes mellitus type II. L-Threose has been shown to have inhibitory properties against sephadex G-100, a membrane protein found in bacteria. L-Threose may be useful as a control agent for research into the response element of polymerase chain reaction (PCR).Title:?L-ThreoseCAS Registry Number:?95-44-3CAS Name:?(2R,3S)-2,3,4-TrihydroxybutanalMolecular Formula:?C4H8O4Molecular Weight:?120.10Percent Composition:?C 40.00%, H 6.71%, O 53.29%Literature References:?By degradation of?L-xylose through the oxime and tetraacetyl-L-xylononitrile to?L-threose diacetamide: Hockett?et al.,?J. Am. Chem. Soc.?60,?278 (1938); from?D-glucitol: Hutson, Weigel,?J. Chem. Soc.?1961,?1546.Properties:?Shows mutarotation; final [a]D20?+13.2? (c = 4.5). Sol in water.Optical Rotation:?[a]D20?+13.2? (c = 4.5)?Derivative Type:?PhenylosazoneMolecular Formula:?C16H18N4O2Molecular Weight:?298.34Percent Composition:?C 64.41%, H 6.08%, N 18.78%, O 10.73%Properties:?Dec 162?.CAS Number95-44-3Product NameL-ThreoseIUPAC Name(2R,3S)-2,3,4-trihydroxybutanalMolecular FormulaC4H8O4Molecular Weight120.1 g/molInChIInChI=1S/C4H8O4/c5-1-3(7)4(8)2-6/h1,3-4,6-8H,2H2/t3-,4-/m0/s1InChI KeyYTBSYETUWUMLBZ-IMJSIDKUSA-NSMILESC(C(C(C=O)O)O)OSynonyms2,3,4-trihydroxybutanal, D-threose, erythrose, erythrose, (R*,S*)-isomer, erythrose, (R-(R*,S*))-isomer, erythrose, (S-(R*,S*))-isomer, L-threose, threoseCanonical SMILESC(C(C(C=O)O)O)OIsomeric SMILESC([C@@H]([C@H](C=O)O)O)O CAS No: 95-44-3 MDL No: MFCD00066540 Chemical Formula: C4H8O4 Molecular Weight: 120.1References: 1. Beil. 1, IV, 4173